Vincristine induced cranial neuropathy.
نویسندگان
چکیده
Neuropathy is a well known side effect of vincristine, however cranial nerve toxicities are reported less frequently which can involve any cranial nerve in mostly bilateral pattern. As many patients have primary tumors or metastatic lesions in sites that could cause the clinician to overlook this reversible cause of neurologic dysfunction, the potential for misdiagnosis is high. Here, along with review of literature we describe three cases on vincristine who developed cranial neuropathy while on treatment.
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Prof. Nuran Akman, MD, Department of Internal Medicine, Cerrahpaşa Medical School, University of Istanbul, TR-34303 Cerrahpaşa/Istanbul (Turkey) Neurotoxicity is a dose-limiting side effect of vincristine. It may be divided into four groups: peripheral neuropathy, autonomic neuropathy, encephalopathy and cranial neuropathy [1]. Cranial nerve palsies are seen less often than peripheral or autono...
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ورودعنوان ژورنال:
- The Journal of the Association of Physicians of India
دوره 60 شماره
صفحات -
تاریخ انتشار 2012